The development and progression of cancer can be defined by several molecular and cellular biological characteristics. In this course, we will utilize primary literature to begin to understand (1) how specific cellular processes are altered during cancer initiation and progression; (2) how different cancers and the genetic landscape underlying them are being studies using models in the laboratory; and (3) how innovative therapeutics are being designed to target tumors based upon their individual molecular signatures.

Principles and technical skills fundamental to the culture of animal cells. Introduction to the techniques of sub-culturing, establishing primary cultures, karyotyping, cloning, growth curves, and cryopreservation. Techniques involving culturing mammalian cells in bioreactors will be introduced. Application of cell culture to contemporary research in biotechnology through independent projects.

Principles and technical skills fundamental to the culture of animal cells. Introduction to the techniques of sub-culturing, establishing primary cultures, karyotyping, cloning, growth curves, and cryopreservation. Techniques involving culturing mammalian cells in bioreactors will be introduced. Application of cell culture to contemporary research in biotechnology through independent projects.

Laboratory course focused on application of molecular biology techniques of the isolation, quantitation, detection, analysis, and use of proteins. Substantial emphasis will be on the use of immunoassays and antibodies in protein work. Modern proteomics techniques will also be discussed. Emphasis will be on recombinant protein expression in the field of biotechnology.