Introduction to fundamental concepts in bioengineering with primary emphasis on understanding details of biomolecular structures integrated with molecular modeling, simulation, and visualization techniques. The course will introduce structural details of various biomolecules (proteins, nucleic-acids, sugars, and lipids), followed by concepts in thermodynamics and physical chemistry (such as intermolecular forces, energy, entropy, chemical potential, and Boltzmann's distribution), the applications of which will be discussed in the context of drug-receptor interactions, molecular recognition, biomolecular folding, enzyme catalysis, allosteric communication, diffusion, and transport. The laboratory will include training and learning about advanced simulation and visualization software engines. Preference will be given to bioengineering majors.

Bioengineering design course will cover safety, regulations and ethics for development of bioengineering devices and processes. Topics include product design, benchmarks, design team functioning, marketing and finances. Students will also learn about current Good Manufacturing Practices, process validation and intellectual property considerations. Students will produce the following documents during the course: preliminary design, materials and supplies list, project schedule and budget, innovation map, FDA approval plan.

Students will learn about the nature and practice of science as it relates to biology, and the ways in which our activities have a biological impact on the world around us. Throughout the course, the students will examine the biological messages with which we are constantly bombarded, and by linking background scientific principles to those messages, practice distinguishing science from pseudoscience.

Introduction to structure and function of cells; tissues and organs; physiological processes; genes and heredity. Required for majors in the biological sciences. Special fee. Lab. Students not permitted to enroll in BIOL 411 and BIOL 412 in the same semester.