In this course students will gain an understanding of the fundamentals of biomaterials, gene therapy, cell therapy, and tissue engineering. We will cover chemical, structural, and biological aspects of therapeutic materials along with systemic literature reviews involving advanced therapy medical products (ATMPs) utilizing molecules, genes, cells, and tissues. We will also discuss synthetic polymers and biomolecules such as peptides, proteins, polysaccharides and oligonucleotides. No credit for students who have taken BIOT 897 "Top/Advanced Therapies".

Laboratory course focused on application of molecular biology techniques of the isolation, quantitation, detection, analysis, and use of proteins. Substantial emphasis will be on the use of immunoassays and antibodies in protein work. Modern proteomics techniques will also be discussed. Emphasis will be on recombinant protein expression in the field of biotechnology. Special Fee.

Introduction to stem cells and how biomaterials are utilized in their applications involving biotechnology and biomedical engineering. Lab topics such as aseptic technique, stem cell cultures, biomaterials engineering, bioprinting, biocompatibility and bioactivity analyses will be covered. Lectures will focus on the current literature while the lab portion involves inquiry-based projects that will investigate how biomaterials and molecules modulate stem cell proliferation and differentiation.

The applied research experience enhances the student's academic achievements with real-world, professional industry projects through placement at biopharma industry organizations. The student is expected to apply knowledge and skills acquired through other coursework in the major to address and solve new, authentic problems identified by the employer. Under the direction of a faculty advisor and workplace supervisor, the student is expected to contribute effectively within a team at the organization.