Principles and technical skills fundamental to the culture of animal cells. Introduction to the techniques of sub-culturing, establishing primary cultures, karyotyping, cloning, growth curves, and cryopreservation. Techniques involving culturing mammalian cells in bioreactors will be introduced. Application of cell culture to contemporary research in biotechnology through independent projects.

In this course, students will gain an understanding of how best to conduct data analysis experiments utilizing data specific to biotechnology applications. Hands-on exercises involve using computer software programs such as Matlab and JMP. Data input/manipulation, descriptive and inferential statistics, hypothesis testing, curve fitting, and Matlab coding will be covered. Upon completion of the course, students should be able to conduct data analysis experiments within the context of biotech. No credit for students who have taken BIOT 897 "Top/Num & Statistical Analysis".

This course will provide the students with an overview of biopharmaceutical production processes through lectures. The course begins by introducing students to the proteins and biotechnology companies and to cGMP. During lab, students will use mammalian cells to produce a monoclonal antibody by developing manufacturing SOPs, including upstream and downstream processing and quality control and assurance. Students will also gain experience with T-cell culture as part of the CAR-T technology utilized in personal medicine.

The applied research experience enhances the student's academic achievements with real-world, professional industry projects through placement at biopharma industry organizations. The student is expected to apply knowledge and skills acquired through other coursework in the major to address and solve new, authentic problems identified by the employer. Under the direction of a faculty advisor and workplace supervisor, the student is expected to contribute effectively within a team at the organization.