This course explores the role of nutrition and the gut microbiota in underlying biochemical, metabolic, and immunological processes of chronic and infectious diseases. The course first provides an overview of organs, systems, metabolic processes, and their modulation by nutrients and the gut microbiota, with a focus on human health. The second half of the course covers the mechanistic links between nutrition, the gut microbiota, and chronic and infectious diseases, where students have an opportunity to apply the concepts learned in the first half of the course. To be successful in this course students will need to have taken courses in biochemistry, nutrition, or nutritional biochemistry, or have instructor permission.